Shin Jie Yong, MSc (Res)
1 min readDec 18, 2020

Slowing down a bit from time to time can be difficult, especially when for people in the 20s trying to make a living...haha.

Anyways, I actually got a difficult question for you, a respiratory medicine professional, if you don't mind.

Do you think lungs in a diseased state (e.g., chronic obstructive pulmonary disease or smoking) may make it harder for SARS-CoV-2 to establish COVID-19? For reasons such as airflow obstruction making it harder for the virus to reach the alveoli, or defective cellular replication machinery for the virus to use. But once it's established, the risk of highly severe COVID-19 and death increases dramatically.

I've also read papers discussing why the prevalence of COPD is rather low among COVID-19 patients. Reasons proposed include underdiagnoses, use of inhaled corticosteroids or bronchodilators, or simply more strict in practicing social distancing may explain the low COPD prevalence among COVID-19 patients. But I was just wondering if the above reasoning seems reasonable.

Shin Jie Yong, MSc (Res)

Named Standford's world top 1% scientists | Independent science writer and researcher | Medium boost program's nominator | Powerlifter with national records