Hmm, thanks for showing me that article. First, I must say that SARS-CoV-2 infection is not limited to the lungs, as the article claimed. SARS-CoV-2 is known to infect other organs, notably the intestines and, to a lesser extent and difficult to prove definitively, the brain and heart. Even the unspecific and excessive immune responses to SARS-CoV-2 in the lungs could harm other organs, but I digress.

Anyway, I must also admit that some cells (e.g., endothelial or other cells) that receive the LNPs could, in theory, produce spike proteins. Such vaccine-derived spike proteins can't bind to ACE2, so point 2 in the linked article shouldn't be a problem.

But point 1 can happen, which is why some cells may get lost or destroyed by the immune system during vaccination. Still, over a million cells die each day in our body as part of normal metabolism. Moreover, assuming that LNPs can cause blood clots near the injection site, our body can dissolve blood clots naturally, provided that those clots are not excessive. (I assumed that blood clots would occur near the injection site because it's unlikely that LNPs can bypass so many endothelial cells that could uptake those LNPs to go to distant sites.) So, I can't really imagine that the mentioned point 1 could be a big problem.