Can the lipid nanoparticles carrying (Covid-19) mRNA vaccine really cross the blood-brain barrier? No, it’s not designed to.
A few researchers have previously raised the hypothetical concern of the Covid-19 mRNA vaccine, encapsulated in lipid nanoparticles (LNPs), entering the brain, given that LNPs can be used to deliver medical drugs across the blood-brain barrier (BBB) into the brain.
I detailed this issue in detail in “Concerns of Lipid…
It’s no longer the pandemic of the unvaccinated. How and why has it come to this point?
The majority of Covid-19 cases are now coming from vaccinated people in several parts of the world with high vaccination rates. Calling it a pandemic of the unvaccinated as we used to is no longer appropriate. Even though the Covid-19 vaccines still work, it is now a pandemic of both…
Newsletter: A short account of the articles published in the past month.
Hello everyone! It’s time for me to send another monthly update on what’s going on in Microbial Instincts, an independent publication about infectious diseases and vaccines that contains nuanced and informative works not easily found elsewhere. …
More questions on the proper injection technique and risk-benefit analysis of mRNA vaccines.
It’s rather uncomfortable to admit that vaccines have health risks, however safe they are in the vast majority. For influenza vaccines, febrile seizures (convulsions), Guillain–Barré syndrome (autoimmune nerve disorder), and anaphylaxis (severe allergic reaction) can happen. …
Although new risks of mRNA vaccines have been discovered, they are not a cause for alarm.
It has been almost a year since the BioNTech-Pfizer’s and Moderna’s mRNA vaccines received emergency use authorization (EUA) from the Food and Drug Administration (FDA) for public use amidst the Covid-19 pandemic in December 2020. …
We can achieve that with natural infection plus vaccination or with mixed vaccinations — so maybe we should rethink how vaccine boosters are given.
Amidst the push for global vaccination to end the Covid-19 pandemic, we have recently discovered the potential of hybrid immunity, the synergistic combination of different forms of immunity. There has probably never been a time where we study immunity so fiercely as the last 12 months. Believe it or not…
A newsletter providing a brief account of articles published in the last month.
Hi all! Here’s another monthly update from me, the editor of Microbial Instincts, an independent publication on Medium. (It’s run by a student, not a professional, but at least he’s politically uninvolved.) …
After going through over 100 research papers, here’s what I’ve found.
In August 2021, Senator Rand Paul of Kentucky said that cloth masks don’t prevent infection from SARS-CoV-2 (that causes Covid-19) in a YouTube video. But Youtube banished the video and suspended Mr. Paul for a week. I got this news from Joe Duncan, a veteran independent writer.
To answer this, we must grasp the interplay between vaccine-induced selection pressure and viral evolution.
There’s an uncanny observation that the SARS-CoV-2 variants of concern (VOCs)— Alpha, Beta, Gamma, and Delta — arose soon after the vaccine clinical trials in the same countries. As a result, some have speculated that the trials instigated the evolution of those VOCs. Let’s see if they have a point.
Variants of concern (VOCs) emergence and vaccine clinical trials
A comprehensive overview of what’s happening and what might happen as we face the evolving coronavirus.
A thought came to my mind: What if a population of unvaccinated and vaccinated hosts creates a selection pressure that selects for the evolution of more dangerous variants than Delta? …
